Hepatitis B e antigen of 0 indicates that the e antigen value is normal, there is no or very little hepatitis B virus in the body, little or no infectiousness, and inactive viral replication. Hepatitis B e antigen is a soluble protein distributed in the core particles of the cellular interstitial space, which is the core part of the hepatitis B virus and may be related to viral replication. So generally speaking, hepatitis B e antigen positive is a sign of infectiousness, the normal value of hepatitis B e antigen is 0 to 0.5 PEIU/ml, so when hepatitis B e antigen is 0, it is normal, indicating that hepatitis B patients are less infectious. When hepatitis B patients with hepatitis B e antigen is 0, patients should go to the hospital in time to do further examination, and combined with the other indicators of hepatitis B five under the guidance of professional doctors for diagnosis and treatment, do not take medication without authorization.