There are many risk factors in life that may lead to cranial defects, such as traffic accidents, falling objects, cranio-cerebral surgery and so on. And cranial defects bring great harm to the body, which requires timely and scientific treatment. As the protective layer of the brain, the skull maintains the normal activity of the brain tissue and allows our body functions to function normally. Cranial defects are very scary, causing patients to have localized swelling and pain, and also causing different degrees of dizziness, headache, memory loss, poor self-control and other symptoms, and more seriously, it will also cause the brain tissue atrophy and cystic degeneration. Based on this danger, cranial defects must be repaired, and it is necessary to choose the right repair material to ensure postoperative recovery. At present, the most widely used repair material is titanium alloy, so many patients can’t help but have questions, titanium alloy repair of the skull has disadvantages, will rust? Some experts answered: it won’t rust, but using titanium alloy as the repair material still has many disadvantages and shortcomings. For example, patients are particularly sensitive to hot and cold reactions after the operation, not daring to sunbathe, there is some slight pain in the edge of the repair, patients can not accept normal medical examination after the operation, and at the same time, the appearance of the effect can not make the patients satisfied. In order to let more patients with cranial defects see the hope of perfect repair, after unremitting efforts, after in-depth exploration, through clinical practice has proved that a new type of material – polyether ether ketone material, also commonly known as PEEK material in the cranial bone as a material for repairing its uniqueness and advancement of its insulation, strength, hardness, elasticity, etc. are the same as the autologous cranial bone, but also the same as the autologous cranial bone. Its heat insulation, strength, hardness, elasticity, etc. are comparable with the autologous skull, and it perfectly restores the anatomical technology of the skull through 3D printing technology, and carries out complex molding, so that it fits perfectly with the edge of the patient’s defects, with excellent cosmetic effect. The application of Peek material is exactly the latest trend in cranial bone repair.