Genital nerve sensitivity can usually be treated with medication and surgery under doctor’s advice. Genital nerve sensitivity may be caused by excessive excitation of genital nerve endings. 1. Drug treatment: patients with sensitive genital nerves can use glutamine tablets, methylcobalamin tablets and other drugs under the guidance of the doctor for treatment, so that the delayed synaptic transmission and neurotransmitter reduction back to normal, after the use of the patient may experience nausea, vomiting, diarrhea and other symptoms, the use of medication should be stopped immediately, the history of allergy to methylcobalamin or any excipients in the prescription of the patient prohibited this drug. 2. Surgical treatment: patients can under the advice of the doctor for dorsal penile nerve block, glans nerve sensitivity desensitization surgery, cut off part of the dorsal penile nerve branches, so as to achieve a reduction in the sensitivity of the genital nerve, 24 hours after the operation to a liquid diet, avoid spicy stimulation and drinking alcohol. Patients should use medicines reasonably under the doctor’s advice and choose the appropriate way for treatment.