Brain infarction is relatively serious in the brainstem, which includes the midbrain, brain bridge and medulla oblongata, and brain infarction in the medulla oblongata is quite serious in all brain infarctions. Because of the severe edema in the medulla oblongata, the patient may experience damage to the respiratory and circulatory centers, which may manifest as respiratory and circulatory arrest, and in severe cases, the patient may die. At the same time, infarction of the cerebral bridge, especially if the area is large, can affect the patient’s superior reticular activation system, and the patient can show impaired consciousness. Patients with brainstem infarcts are often associated with choking on water and swallowing difficulties, and due to poor feeding, patients can suffer from malnutrition and intrapulmonary infections caused by aspiration. Brain infarction in the brainstem is a clinically serious infarction, and patients should be given active treatment during the acute stage, including thrombolysis, antiplatelet aggregation, and drugs to remove oxygen free radicals and activate blood stasis.