Anacin belongs to the non-steroidal class of antipyretic and analgesic drugs, because of the serious side effects of this drug, is rarely used in clinical practice, almost all do not choose to apply, so high fever needs to use drugs to reduce fever, are not used as the drug of choice. The side effects of Anacin: first, can cause granulocyte deficiency, often acute onset, easily fatal, can also cause autoimmune hemolytic anemia, as well as thrombocytopenic purpura and reoccurrence. Secondly, it can cause drug-related liver and kidney damage, and there may be acute liver and kidney failure, even life-threatening. Thirdly, it can cause allergy, especially acute urticaria, severe deprivation dermatitis, and even anaphylactic shock leading to death. Therefore, in clinical practice, if it is necessary to reduce fever by drugs, it is recommended to choose other non-steroidal drugs, like ibuprofen, acetaminophen are safer.