The spinal pain in the center of the back can be caused by the following reasons: first, tumor, when there is a tumor or metastatic tumor in the spine, there can be pain in the spine, especially when the pain is more obvious in the night time, and it can be accompanied by systemic symptoms, such as low-grade fever and lethargy, and it is necessary to take CT, ECT, and MRI of the spine at an early stage to make early diagnosis and treatment. Second, osteoporosis, severe osteoporosis can appear spinal pain, pain is more obvious when there is a compression fracture, early X-ray film of the spine, CT examination, as well as blood tests to diagnose, if necessary, to the endocrinology department for the diagnosis of the original disease. Third, degeneration of the spine, spinal degeneration can also occur when the spine pain, early X-ray film of the spine, CT examination, to early diagnosis. Fourth, rheumatoid and ankylosing spondylitis, can also appear spinal pain, can be accompanied by stiffness, sacroiliac joint pain, early blood tests, as well as X-ray film of the spine, magnetic resonance imaging to early diagnosis.