Pain in the muscles of the front of the thigh suggests that there may be inflammation or trauma around the quadriceps muscle, often seen in the following diseases: 1, there is injury to the quadriceps muscle, this condition is common when there is a direct impact against the front of the thigh or there is a pulling type of injury, these injuries often cause inflammation of the quadriceps muscle, edema, or even tearing of the muscle belly. The condition can lead to severe pain in the anterior thigh and severe limitation of lower limb movement. 2. It may be caused by fatigue of the quadriceps muscle, which may produce a large amount of lactic acid deposition inside the quadriceps muscle after squatting, running, jumping or heavy weight bearing activities, and then cause soreness of the entire muscle. 3. The presence of a herniated lumbar disc or the presence of the femoral nerve or lateral femoral cutaneous nerve compression, etc., may produce radioactive pain in this area.