In everyday life, it is common for patients to experience pain in the calf muscles when they exercise. When this phenomenon occurs, there are many causes that can lead to it. The first thing to consider is whether the patient is suffering from soft tissue damage and excessive lactic acid accumulation in the calf muscles due to excessive exercise, which leads to muscle pain. If this is the case, the patient can be asked to rest in bed, avoid strenuous activities, avoid local cold, and can be combined with Chinese medicine massage and topical ointment to activate blood circulation and remove blood stasis. After the correct treatment, the symptoms will be gradually relieved in a week or so. In addition, we should consider whether the patient is suffering from popliteal cyst, and then add the excessive activity of the calf, resulting in the cyst compressing the tibial nerve and tibial artery, and the muscle pain in the calf area, we can do ultrasound examination of the calf, which can clarify the location and size of the cyst, and then consider taking the corresponding treatment.