Symptoms of bouts of pain in the liver area may be related to hepatitis B, cirrhosis, cholecystitis, gallstones, etc. The cause of the disease should be determined before treatment. 1. Hepatitis B: Patients with hepatitis B virus infection leading to hepatitis B may experience symptoms such as loss of appetite, fluttering pain in the liver area, and fatigue. 2. Cirrhosis: Patients with diffuse fibrosis of liver tissue and cirrhosis caused by hepatitis B virus infection, autoimmune liver disease, or heavy drinking over the years may have symptoms such as weight loss, fatigue, diarrhea, and bouts of pain in the liver area. 3. Cholecystitis: After cholecystitis caused by obstruction of gallbladder stones or infection, patients may have symptoms such as dull pain in the right upper abdomen, nausea and vomiting. 4. Choledocholithiasis: Patients with choledocholithiasis caused by too much cholesterol in the bile may have symptoms such as a sharp pain in the upper right liver area, bloating, belching (hiccups), nausea, etc. This may lead to a prolonged bout of pain in the liver area. There are many causes of prolonged bouts of pain in the liver area, so it is important to go to the hospital to determine the cause of the pain and then treat it appropriately.