Pressing pain in the left lower abdomen may be caused by left hemicolon disease, left ureteral stone, left adnexitis and so on. 1. Left colon disease: such as descending colitis, sigmoid colitis, proctitis, sigmoid colon cancer and other diseases, can lead to left lower abdominal pressure pain. 2. Left ureteral stone: it is the stone occurring in the left ureter, which can also lead to left lower abdominal pressure pain, usually accompanied by lumbar cramps, hematuria and other symptoms. 3. Left-sided adnexitis: refers to the inflammation that occurs in the left fallopian tube and ovary, which can also lead to pressure pain in the left lower abdomen, accompanied by fever, lower abdominal swelling, lumbosacral pain, leukorrhea, menstrual disorders and other symptoms. There are many other causes of left-sided lower abdominal pain on pressure, which should be taken seriously, and timely consultation should be made to identify the cause of the disease and further treatment or therapy as prescribed by the doctor.