The yellowing of urine that can occur after oral administration of vitamin B preparations is a normal staining phenomenon and is not a disease condition. After oral intake of vitamin B preparations, some of them are absorbed and some of them are excreted in their original form through urine, which can be manifested as yellow coloring of urine. The color of urine can be restored to normal after the drug intake is stopped, so there is no need to worry. It is recommended to take vitamin B preparations and drink more water and urinate more often, keeping the daily water intake above 1500ml. If the body is not deficient in the relevant vitamin preparations, it is sufficient to stop the intake of the relevant drugs, or to stop the drug after the treatment course is sufficient, the color of urine can be restored to normal. Clinically, many drugs can stain after oral administration, except vitamin B preparations, such as oral administration of more antibacterial agents, such as sulfonamide antibiotics or furan antibiotics, etc., can appear after taking the drug yellow urine color phenomenon. These are normal phenomena, not a state of disease.