Postoperative chemotherapy regimens for stage III gastric cancer mainly include FOLFOX,XELOX,SOX and DS sequential S-1 regimens, and the specific chemotherapy regimen needs to be formulated according to the specific conditions of patients. 1. FOLFOX regimen: oxaliplatin + fluorouracil + calcium folinate. 2. XELOX program: oxaliplatin + capecitabine. 3.SOX regimen: oxaliplatin + Tegio. 4.DS sequential S-1 regimen: Tegio + docetaxel. Of course, chemotherapy has corresponding adverse reactions, which should be closely watched, early detection and early treatment. Therefore, patients with stage 3 gastric cancer need surgery combined with chemotherapy, and chemotherapy needs to be selected according to the specific conditions of patients, and patients should not take drugs by themselves. After chemotherapy, patients need to have regular review according to doctor’s arrangement in order to prevent recurrence. If recurrence occurs, patients should go to hospital for treatment in time.