If a diabetic patient has numbness in the toes, it often indicates peripheral neuropathy. 1. The most critical thing in this case is to control blood sugar, which is the first and foremost treatment measure. 2. The purpose is to prevent the formation of blood clots and to promote the improvement of nerve circulation. If the patient’s toe numbness is still not relieved in time by these measures, it is necessary to improve the relevant cranial examination to assess whether the patient’s numbness is caused by the central nervous system.