If a diabetic patient finds a black toe, the most critical thing is to treat it in a timely manner: 1. The first point of treatment is to assess the condition in a timely manner, because a black toe often indicates the occurrence of a diabetic foot, and this occurrence may have produced gangrene necrosis, the most critical treatment in this case is anti-infection and amputation of the toe, only then can the infection foci be lifted from the root, so as to prevent the spread of the foci to the whole body to form a serious infection. This is the most critical point of treatment. 2, control of blood sugar, in this case blood sugar control often requires the initiation of insulin therapy. This is because many patients with severe diabetic foot can not take oral hypoglycemic drugs, this must be clear, insulin treatment involves insulin intensive treatment program and insulin premixed treatment program. 3, to use nerve nutrition and improve microcirculation drugs, only in this way can maximize the improvement of the patient’s toe nerve function and circulation function, so that the condition is more conducive to recovery and control.