Pressing pain in the breast near the armpit may be related to injury, inflammation, paratesticular breast, breast cancer and other conditions. 1. Injury: if the patient has recently done more chest exercise or daily physical labor, there may also be trauma in the axillary region, which may lead to local soft tissue injury, resulting in pain on pressure. 2. Inflammation: mainly seen in lymphadenitis, due to the rich lymph node tissue in the axillary region. If the patient has infectious lesions in the chest, breast, upper limbs and neck area, it may lead to local lymphadenitis and pain on pressure. 3. Associate breast: It is a lesion caused by abnormal breast discovery, due to incomplete degradation of the breast primordium, forming associate breast lesion, which mostly occurs in the axillary region. Some patients may have pain when pressing on it. 4. Breast cancer: it is a common malignant lesion of the breast, as most patients can have lymph node metastasis in the axillary region, when the lesion metastasis occurs, there may be axillary pressure pain. In addition, breast hyperplasia, cardiothoracic diseases, herpes zoster may also appear in the above clinical manifestations, which require patients to seek medical treatment as early as possible to confirm the diagnosis of the lesion, and then combined with the nature of the lesion and the clinical symptoms, to carry out the corresponding treatment.