Ventricular septal defect plus pulmonary hypertension can be treated by interventional therapy and surgery. 1. Interventional therapy: For ventricular septal defect plus mild to moderate pulmonary hypertension without right-to-left shunt, catheter intervention can be used to seal the defect by puncturing the femoral artery or femoral vein, and using a special catheter to deliver the sealer from the peripheral vasculature to the site of the ventricular septal defect and repair it, which can alleviate the pulmonary arterial hypertension while treating the ventricular septal defect. 2. Surgery: mainly open-heart surgery, the repair of ventricular septal defects under extracorporeal circulation with direct visualization of the heart can also achieve the purpose of relieving pulmonary hypertension, but those with pulmonary vascular resistance > 7 Wood units should not be operated. If ventricular septal defect plus pulmonary arterial hypertension, you should seek timely medical treatment and choose the appropriate treatment under the advice of your doctor.