HIV positive and weak positive generally speaking, for clinical judgment of AIDS is not much difference, because the follow-up are required to do further confirmatory tests, should be subject to the results of confirmatory tests. HIV positive and weak positive, refers to the initial screening test HIV antibody is positive or weak positive, but can not carry out the diagnosis of AIDS, the follow-up need to do further HIV confirmatory tests. If the confirmatory test is positive, then it can be clearly diagnosed as infected with HIV; if the confirmatory test is negative, regardless of whether the initial screening is positive or weakly positive, generally cannot diagnose AIDS. However, it should be noted that for those who are positive or weakly positive for HIV in the initial screening but negative in the confirmatory test, it is recommended that they be retested after three months under the guidance of a doctor if they have had high-risk sexual behavior.