Endocrine disorders are hormonal changes that refer to certain types of diseases, such as thyroid hormone disorders causing hyperthyroidism and hypothyroidism, sex hormone disorders causing breast development, impotence and premature ejaculation. It is necessary to listen to the professional doctor’s opinion and give treatment according to the specific disease. For example, hyperthyroidism can appear irritability, diarrhea, palpitations, fatigue and other symptoms. Usually male endocrine disorders have their own specific diseases with different manifestations, endocrine disorders itself is not a disease, so there is no fixed clinical manifestations. When male androgen secretion decreases or estrogen increases, there will be delicate skin, abnormal penile development, or impotence and premature ejaculation and other clinical manifestations, and some patients will have unilateral or bilateral breast development. If endocrine disorders occur, it is recommended to consult a doctor in a timely manner, follow the doctor’s instructions for treatment, do not abuse drugs.