Cystitis combined with prostate enlargement needs to be treated separately for both diseases, anti-infective treatment is feasible for cystitis, and medication or surgery is feasible for prostate enlargement. Cystitis belongs to the lower urinary tract infection, is an infectious disease, mostly caused by bacterial infection. Treatment is based on anti-infection, commonly used broad-spectrum antibiotics, such as ofloxacin, ciprofloxacin, etc., to be clarified after the results of drug sensitivity and then sensitive drug treatment. When the symptoms of prostate enlargement are mild, observation is the main focus. When clinical symptoms such as frequent urination, delayed urination and interrupted urination occur, alpha receptor blockers such as terazosin and alfuzosin can be used for treatment. Surgery, such as transurethral resection of the prostate, suprapubic transcystic or retropubic resection of the prostate, is feasible when symptoms are severe and obstruction is present. Specific treatment varies according to the condition, it is recommended to consult a doctor in a timely manner, follow the doctor’s instructions for standardized treatment, and consult a doctor before using medication.