The back of the hand peeling and white flakes to consider with dry weather, tinea versicolor, hand eczema and other factors related to the treatment should be taken according to the cause of its moisturizing, antifungal, anti-inflammatory and other treatments. 1. Dry weather: especially in the fall and winter seasons, due to the dry weather, the stratum corneum dehydration shedding, patients often appear on the back of the hand peeling and other dry skin manifestations, at this time you can apply hand cream and other moisturizing skin. 2. Ringworm: for patients with ringworm, due to localized fungal infections, so patients will appear local erythema, papules, blisters, flaking and other manifestations, this time to comply with the doctor’s instructions to use miconazole, terbinafine, fluconazole and other antifungal preparations for treatment. 3. Hand eczema: for patients with hand eczema, due to the local combination of inflammatory stimuli, so the patient will appear symmetrical distribution of papules, blisters, vesicles and other polymorphic lesions, accompanied by obvious itching, for the local skinned patients can be prescribed the use of urea ointment topical, combined with the furoate mometasone ointment and other glucocorticoid drugs topical. For the back of the hand peeling and white flakes of patients, it is recommended that they go to the regular hospital dermatology department, clear cause of the disease in the doctor’s guidance and active treatment.