There is no such thing as the “most effective” way to get rid of acne. Depending on the individual’s situation, common methods include general treatment, topical medication, and systemic medication. Acne, clinically known as acne, is a chronic inflammatory disease of the sebaceous gland units of the hair follicles, most common in adolescents, and is associated with genetics, androgens, Propionibacterium acnes, and immune factors. The treatment of acne should follow the principle of individualization, and there is no so-called “most effective” method. Commonly used treatments include general treatment, topical medication, systemic medication, and adjuvant therapy. 1. General treatment: including choosing the right cleansing products, do not over wash, do not squeeze, scratch the rash, can reduce the intake of sugar, milk, do not stay up all night. 2. Medication: Vitamin A acid cream, benzoyl peroxide gel, antibiotic preparations such as fusidic acid cream, etc.; systemic medication includes antibiotics such as doxycycline, minocycline, and isotretinoin. 3. Auxiliary treatments: chemical peeling treatment such as fruit acid skin resurfacing, fractional laser treatment for acne scarring, etc. Acne is recommended to be carried out under the guidance of a professional dermatologist, and the above medications should be used in accordance with the doctor’s instructions, do not blindly use medication.