Infants and children with acute necrotizing enterocolitis have atypical symptoms, with the onset of the disease in the first 3 to 10 days of life. Admitted to the ward due to prematurity or low birth weight, retention in the stomach is found during artificial feeding or during nasal feeding with a gastric tube placed in immature children due to incomplete establishment of the swallowing reflex, followed by signs such as abdominal distention, vomiting, blood in the stool fever or failure to increase body temperature, tachycardia or slow heart rate, abdominal muscle tension, abdominal distention, and erythema of the abdominal wall. The disease lacks specific diagnostic features and varies in severity, especially in non-prone areas, and is more likely to be misdiagnosed, with a misdiagnosis rate of 50% to 60%. The main clinical diagnosis is based on the following: 1. The possibility of the disease should be considered in those who have a history of unclean diet, onset in summer and autumn, sudden onset of severe abdominal pain, diarrhea and fishy smelling blood in the stool, nausea and vomiting, and obvious symptoms of poisoning. 2, according to the stage of the disease and the patient’s performance, different clinical types are distinguished: diarrhea and bloody stool type, with diarrhea and blood in stool as the main manifestation; peritonitis type, mainly showing signs of mesenteritis; poisoning type, with shock as the prominent manifestation or with DIC; intestinal obstruction type, with the characteristics of acute intestinal obstruction as the main manifestation. Abdominal pain with hematuria: abdominal pain with hematuria is one of the clinical manifestations of kidney and ureteral stones. Abdominal type obesity: people with apple type figure have excessive fat waist and abdomen, resembling apple, thin arms and legs and big stomach, also called abdominal type obesity. Stabbing pain in the abdomen: The common symptom of gynecological disease of stabbing pain in the abdomen brings great pain to the patient, and sometimes the pain is unbearable. There are many kinds of pain in the abdomen and many causes. The treatment of acute necrotizing enterocolitis requires close cooperation between medical and surgical doctors, and the progress of the disease should be carefully and carefully observed during the adoption of medical treatment, and the detection of all relevant indicators should be strengthened. Surgical operation is only one of the treatment methods, and post-surgical management is more important.