The effect of bioimmunotherapy is still better. When malignant tumors are advanced, such as lung cancer is advanced, distant metastasis has occurred, and other treatment methods, such as radiotherapy, chemotherapy and targeted therapy, are not effective, bioimmunotherapy can be used, which can significantly improve the patient’s symptoms, and the efficiency can reach about 50%. Therefore, for the comprehensive treatment of malignant tumor, bioimmunotherapy is also a part of the comprehensive treatment. When other methods are poor, bioimmunotherapy can be used to improve patients’ quality of life.