Acute gastritis is very common in life, mostly seen in overeating and binge drinking, or eating drugs that tend to irritate the gastric mucosa, such as taking aspirin, ibuprofen, or pau d’arco, there is a risk of acute gastric mucosal inflammation, which can manifest as acute gastritis. Clinically, abdominal pain, nausea and vomiting inability to eat can occur. At this time, drugs for gastritis need to be given promptly under the guidance of a doctor. Acute gastritis should be actively treated for the primary cause, first by removing the possible causative factors. General therapeutic drugs include gastric mucosal protective agents and acid suppressants. In general, patients with mild cases can be given gastric mucosal protective agents such as Almagate, Thioglycollate, Rebaft, H2 receptor antagonists, etc., while severe patients can be given proton pump inhibitors. For taking drugs such as aspirin enteric tablets can be used, taken with meals, and mucosal protectors or small doses of H2 receptor antagonists can be added. For patients with acute gastritis due to H. pylori infection, H. pylori eradication quadruple drug (2 antibiotics + 1 proton pump inhibitor + 1 bismuth agent) eradication therapy is given. While using medication, you should eat a light, nutritious and easy-to-digest diet, and try not to eat any spicy, cold, rough or indigestible food, otherwise it may lead to gastric mucosa irritation and aggravation of gastritis, or induce gastritis. In short, paying attention to good diet and taking the right medication is the key to preventing acute gastritis.