Newborns with black fingertips and shortness of breath may have congenital heart disease, and it is recommended to go to the hospital for examination. Congenital heart disease is mainly caused by abnormal development of the heart and large blood vessels during the embryonic period, which may be related to genetic, maternal and environmental factors, including atrial septal defect, ventricular septal defect, arterial ductus arteriosus, tetralogy of Fallot and so on. Newborns with black fingertips and shortness of breath indicate poor circulation and inadequate pumping of blood back to the heart, or venous blood entering arterial blood through abnormal channels. Newborns with black fingertips and shortness of breath may also have other causes, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy.