In general, you can take cephalosporin antibiotics for treatment only after 72 hours after drinking. Most drugs have a certain half-life in the body, and alcohol also has a certain metabolic time in the body, and often after 72 hours, most of the alcohol in the body can be metabolized cleanly and will not have a disulfiram reaction with cephalosporins. Otherwise, if you take cephalosporin after drinking alcohol for a few hours, it is very dangerous and disulfiram-like reactions can easily occur, which means that if you drink alcohol after taking the drug, facial flushing, conjunctival and mucosal congestion will occur. Sometimes some people also experience more severe headaches, dizziness, nausea, vomiting, and violent activity of the blood vessels in the head and neck. Some people are more serious and also experience myocardial infarction, chest pain, and even heart failure, respiratory distress, and acute liver injury, all of which are very dangerous and can lead to death. Therefore, it is safer to wait until 72 hours after drinking alcohol before taking cephalosporins.