If you have small, itchy blisters on your feet and hands, there are two main problems to consider: First, eczema on the hands and feet, which often has blister-like manifestations and is often symmetrically distributed and itchy, is treated mainly with glucocorticoid anti-inflammatory and anti-itch medications. However, ringworm is a fungal infection, and treatment requires antifungal medications and fungal microscopy to detect mycelium or spores. Tinea capitis often starts on one hand or foot and gradually spreads to the other hand or foot.