Numbness is a sensory disorder. It is more common to see thalamic lesions. The thalamus is the relay station of sensation, and after the occurrence of lesions, people mainly have abnormal sensation, such as numbness, pain in the limbs, and individual patients may also have anthroposis. Numbness can also be caused by compression of nerve roots, mostly in cervical and lumbar disc herniation, which can affect the nerves and cause numbness in patients. More commonly, when the sciatic nerve is compressed, a person may experience numbness in the back of the legs and feet. Numbness can also be seen in peripheral neuropathy, mainly due to damage to the peripheral nerves, the peripheral nerves appear demyelination-like changes, the patient can appear numbness at the end of the extremities, and in severe cases, pain. Numbness can also be seen in autonomic dysfunction, such as Raynaud’s disease, where the patient may experience numbness in the end of the hand and a change in finger color.