Perifollicular keratosis granulosa refers to the keratin plugs at the top of keratinized hair follicles in perifollicular keratosis, which can be treated with topical retinoic acid ointment and other treatments under the guidance of a dermatologist, and oral vitamin A, etc., if necessary. Perifollicular keratosis, also known as hair moss, is a chronic follicular keratotic skin disease that manifests itself as pinpoint to corn-grain sized follicular papules, which may be topped with light brown keratin plugs containing curly hairs. Perifollicular keratosis generally requires no specific treatment. It can be softened and dissolved with local topical medications such as retinoic acid ointment, tazarotene gel, 3%~5% salicylic acid ointment, and urea cream. When the disease is serious, you can take oral vitamin A, vitamin E, vitamin A acid and other drugs. All of the above drugs should be used under the guidance of a doctor.