Pediatric liver and kidney bad performance need to be discussed separately, as follows: 1, liver bad, in pediatrics is mainly a variety of infections, poisoning caused by liver injury or toxic hepatitis, hepatitis B, hepatitis A and so on. Clinical manifestations can be jaundice, loss of appetite or anorexia, dyspepsia, nausea, vomiting, pain in the liver area, liver function tests can be seen as elevated aminotransferases, as well as a reduction in total protein, albumin, and bilirubin elevation to straight bile is predominantly high; 2, pediatric kidney is not good, including acute and chronic nephritis, urinary tract infections, etc., the clinical manifestations of the eyelids may be swollen, urinary oliguria or hematuria, proteinuria, blood pressure, elevated blood pressure, urinary tract infections. Urinary tract infection manifested as frequent urination, urinary urgency, painful urination, sometimes accompanied by fever, urine routine examination of leukocytes increase mainly, urine culture can sometimes culture gram-negative bacilli. Liver and kidneys are organs for detoxification and elimination of toxins, and food and drug poisoning can easily involve them.