The severity of sinus rhythm ST changes depends on the presence of serious organic diseases, simple ST changes are not serious, combined with serious diseases in patients with serious conditions. Sinus rhythm ST changes in the clinic is relatively common, can be seen in the normal population, in addition to the patient does not have serious organic disease, the condition is not serious. Some patients with ST segment changes may have organic diseases, such as coronary artery disease, rheumatic heart disease, ischemic cardiomyopathy, etc. Some patients may have diseases other than the heart, such as severe anemia, chronic obstructive pulmonary disease, etc., and the severity of the condition will be significantly increased, and there may even be serious complications. Patients with alterations in sinus rhythm ST are advised to consult a hospital in time to clarify the cause and standardize treatment under the guidance of a physician if necessary.