Generally speaking, antibodies can be checked 30 days after hepatitis B vaccination. People can go to the hospital after 30 days of hepatitis B vaccination to review the hepatitis B penta-analysis to check the antibody, if the result of the hospital examination shows that the surface antibody of hepatitis B is positive, then it indicates that the antibody exists in the body; if the result is negative, the organism needs to be vaccinated again. However, people should pay attention to the hepatitis B vaccine should be standardized throughout the vaccination, otherwise it can not play a role in preventing hepatitis B. Normal hepatitis B vaccine needs to be injected three times in the hospital, and if the patient does not produce antibodies after the third injection, it is recommended that the patient go to the hospital to get another injection in a timely manner. However, if the patient has been infected with hepatitis B, the hepatitis B vaccination will have no preventive effect. For the people who have been vaccinated with hepatitis B vaccine, they should pay close attention to their own situation, and inform the hospital in time when there are uncomfortable symptoms, so as not to miss the optimal time for vaccination.