The severity of leukoaraiosis depends mainly on the degree of involvement of internal organ systems and cannot be generalized. Leukoaraiosis is an autoimmune disease that may involve multiple systems and organs, and is common in patients with immune disorders. If the symptoms of leukemia are mild, involving only conjunctivitis, mouth ulcers, or genital ulcers, and do not involve the integumentary system, it is not serious. It is more serious if leukosis invades the visceral system and causes gastrointestinal ulcers, abdominal pain, bleeding, etc., or if it involves the brain or large blood vessels, etc., resulting in impaired consciousness, sensory disorders, erratic behavior, hemiparesis, blood clots or pulmonary hypertension. Once the symptoms of leukoaraiosis appear, it is recommended to go to the rheumatology and immunology department of regular hospitals as soon as possible, cooperate with professional doctors to conduct examinations, make a clear diagnosis, and carry out timely treatment to actively control the condition.