High amyloid A is commonly seen in acute phase reactions, that is, acute viral, bacterial, chlamydial, mycoplasma and other infections. When the body is invaded by pathogens in the acute phase, the liver synthesizes a large amount of amyloid A and releases it into the blood, causing an increase, and when the infection is controlled, the corresponding amyloid A decreases again. Therefore, amyloid A is a very sensitive indicator, appearing earlier and better reflecting the inflammatory response process than C-reactive protein. Of course, amyloid A can also be elevated in certain other conditions, such as tuberculosis, leprosy, rheumatoid arthritis, rejection after transplantation, and certain malignancies, which may lead to increased amyloid A. Therefore, further detailed examination is needed to rule out related problems.