Monkeypox can be transmitted through the respiratory tract, the digestive tract, and through contact. Monkeypox is mainly caused by infection with the monkeypox virus, which can be transmitted through the respiratory tract, digestive tract and contact, and the main sources of infection are host animals, infected animals, and patients with monkeypox. For example, susceptible people may be infected with monkeypox virus by prolonged contact with monkeypox patients or contact with their virus-contaminated items, as well as by bites from infected animals and consumption of virus-contaminated food. When the virus enters the human body, it can spread to the mucous membranes, skin and other tissues throughout the body through the bloodstream, thus causing corresponding lesions and symptoms such as rash, herpes, fever, muscle aches and pains. Monkeypox is highly contagious and requires appropriate isolation treatment once diagnosed. Most of the patients can be self-healed or cured after active treatment. Patients can develop immunity after healing and usually will not recur. However, in severe cases, irreversible damage may occur and death may result. During monkeypox virus epidemics, care should be taken to increase awareness of personal protection, avoid close contact with sick animals or monkeypox patients, and also through smallpox vaccination.