Soreness in the tibialis anterior muscle of the calf should be treated with different measures depending on the cause of the soreness, such as taking rest, hot compresses, oral medication and surgery. If the calf tibialis anterior muscle is too fatigued after intense exercise such as running and climbing, soreness will occur. You should pay attention to proper rest, and you can promote blood circulation and lactic acid metabolism to relieve the pain by scalding with warm water, hot compresses with hot water bags, and massage. If the calf muscle soreness is caused by trauma, pay attention to proper rest, you can take anti-inflammatory analgesic drugs such as nimesulide, diclofenac sodium for treatment. If it is caused by osteochondritis dissecans, it can be treated by hot compresses and oral anti-inflammatory and analgesic drugs such as nimesulide and diclofenac sodium. If it is caused by tibial tumor such as tibial osteosarcoma, it can be treated by surgical resection. If the symptoms of tibialis anterior muscle soreness in the lower leg occur, it is recommended that the patient go to the hospital to clarify the cause of the disease and receive regular treatment.