Chronic gastritis needs to be medicated according to the specific causes and symptoms, and there is no such thing as the most effective. Commonly used drugs include acid inhibitors, gastric stimulants, gastric mucosal protectants and so on. 1. Acid-suppressing drugs: these drugs can inhibit gastric acid secretion, which can relieve the patient’s epigastric burning sensation. Commonly used drugs include omeprazole and other proton pump inhibitors, ranitidine and other Hâ‚‚ receptor antagonists. 2. Gastric stimulants: if accompanied by bloating, nausea, abdominal distension, etc., gastrointestinal stimulants such as domperidone can be used. 3. Gastric mucosal protective agents: patients with bile reflux can use gastric mucosal protective agents such as misoprostol and magnesium aluminum carbonate. 4. Hp eradication therapy: if combined with Helicobacter pylori infection, need to be treated by quadruple therapy, including proton pump inhibitors (such as omeprazole, etc.), bismuth (such as bismuth pectin, etc.), and two kinds of antimicrobial drugs (amoxicillin, clarithromycin, etc.). Confirmed diagnosis of chronic gastritis need to be under the guidance of a physician according to the specific condition of the medication, do not self-medication, such as discomfort, please go to the hospital in a timely manner to seek medical attention.