Lung adenocarcinoma stage III, i.e. lung adenocarcinoma stage III, can be cured in a few patients, and the 5-year survival rate of stage III patients is about 15%. It is recommended that patients take timely treatment such as surgery, chemotherapy, radiotherapy and targeted therapy. Patients with stage III lung adenocarcinoma generally belong to advanced stage, and a few patients may be clinically cured after comprehensive treatment. The five-year survival rate of patients with stage III lung adenocarcinoma is about 15%, and patients should follow the doctor’s prescription for treatment. The main treatment for patients with stage III lung adenocarcinoma is surgery, which includes partial lobectomy, lobectomy, total lung resection and other surgical methods. Patients can also take chemotherapy as prescribed by doctors, and the main use includes pemetrexed disodium injection, vincristine injection, paclitaxel injection, gemcitabine injection, cisplatin injection and so on. In addition, patients with stage III lung adenocarcinoma can also take radiotherapy measures, including radical radiotherapy, palliative radiotherapy and comprehensive radiotherapy. Patients can also use targeted drugs such as alectinib hydrochloride capsule, crizotinib capsule, crizotinib capsule and other targeted drugs as prescribed by doctors. Patients with stage III lung adenocarcinoma generally cannot be cured, and it is recommended that they should seek medical treatment in time. Patients should follow the doctor’s prescription for treatment and should not use drugs without authorization.