There is no optimal solution for the treatment of neurodermatitis, which can be solved by the following methods, such as medication, removing triggering factors, and adjusting the mental state. 1.Medication. (1) Topical ointment: neurodermatitis can lead to skin thickening, itching and other symptoms, can follow the doctor’s instructions to choose the topical drug treatment, glucocorticoid preparations such as dianabed cream, fluticasone propionate cream and so on. (2) Oral medication: patients can take antihistamines, such as loratadine, benadryl, etc., which can help relieve the symptoms of itching. 2. Remove the triggering factors: avoid using irritating toiletries, avoid using hot water when bathing, avoid friction, avoid too wet or dry skin, etc., and do a good job of skin moisturizing. 3. Adjust the mental state: improve the quality of sleep, reduce your psychological pressure, relieve the mental burden, do not give yourself too much pressure. Neurodermatitis is prone to recurring attacks, and it is recommended to follow the doctor’s instructions in time to avoid the deterioration of the condition affecting their own health.