Antipyretic and analgesic anti-inflammatory drugs: antipyretic and analgesic anti-inflammatory drugs are a class of drugs with antipyretic, analgesic, most of them also have anti-inflammatory and anti-rheumatic effects. Because of its chemical structure and anti-inflammatory mechanism and glucocorticoid steroidal anti-inflammatory drugs are different, it is also known as non-steroidal anti-inflammatory drugs. Commonly used are aspirin, anti-inflammatory pain, POTASONE, paracetamol, fenpropidone, etc. The pain-relieving effect is relatively weak, and there are mainly side effects on the gastrointestinal tract. Although they are not addictive, they can cause unnecessary damage if not used properly. Because of the wide range of use, clinically reported adverse reactions to painkillers are mainly caused by this class of drugs. Central painkillers: non-opioid central analgesic drugs, represented by tramadol, are classified as non-narcotic painkillers because the mechanism of pain relief is not exactly the same as that of opioids. Tramadol’s analgesic effect is weak, about one-tenth of morphine. It is mainly used for various acute pains of moderate severity and post-surgical pain, etc. Overdose can cause dependence! Adverse effects such as sweating, dizziness, nausea, vomiting, dry mouth and fatigue are present. Narcotic painkillers: represented by opioids such as morphine and dulcolax. This type of drug pain relieving effect is very strong, mainly used for medium to severe pain treatment, such as cancer pain, but repeated use will be addictive! The state has a strict management system for this type of drug, and it cannot be used casually. Reasonable use is the key, at present, life commonly used painkillers are mainly aspirin and fen-phen, etc., such drugs have the possibility of causing gastric hemorrhage, so patients with serious gastric disease is not suitable for use, in addition, renal function is not good patients should also be used with caution; central painkillers for the gastrointestinal tract stimulation of the smaller, less addictive, suitable for patients with gastric disease, but this kind of drug is stronger pain relieving effect, generally not as the Preferred; opioid painkillers, such as dulcolax, morphine, etc., this kind of drug analgesic effect is strong, there is a strong addictive, generally only used for patients with advanced cancer pain. In addition, painkillers will produce certain side effects, so in addition to the type of drug, dose, route of administration and time of administration should be correctly mastered according to the doctor’s instructions, but also pay attention to the use of drugs should be gradually increased from a small dose, to reduce the adverse reactions, when the pain is reduced, the amount of drugs can be gradually reduced. Judge the efficacy of a pain medication, generally to 3 to 5 days whether the effect shall prevail. Painkillers are not scary, antipyretic analgesic anti-inflammatory drugs and central painkillers are not addictive. Only opioid pain medications are addictive with repeated use. Chronic pain patients will not become addicted as long as they undergo standardized treatment in a specialized pain department and use medication under the guidance of a doctor. Painkiller addiction is categorized into somatic and mental. Physical dependence exists with any drug, while mental dependence occurs when painkillers are used for improper purposes. Painkillers can be used safely as long as the patient uses them appropriately under the guidance of a doctor. Abuse of painkillers has serious consequences, if there is a certain kind of pain, it is best not to blindly take painkillers indiscriminately, but to go to the hospital as soon as possible to ask the doctor to identify the cause of the disease, symptomatic treatment. A lot of pain, especially the pain of internal organs, it is difficult for patients to identify what exactly is wrong. If blindly and prematurely take painkillers, although it can temporarily relieve the pain, but due to the painkillers masked the location and nature of the pain, is not conducive to the doctor’s observation of the condition and determine the location of the disease, and is not conducive to the doctor’s correct diagnosis and timely treatment. In addition, after taking painkillers, patients temporarily feel no pain, but in fact, the disease may be in further deterioration, such as ectopic pregnancy hemorrhage, appendicitis secondary necrosis and perforation, this temporary pain will cover the real condition, will make the disease development aggravated, resulting in serious consequences.