Chronic atrophic gastritis can be treated with general treatment, eradication of Helicobacter pylori treatment, surgical treatment and so on. 1. General treatment: For patients with chronic atrophic gastritis, routine treatment is needed as for other gastric patients, using gastric mucosal protection drugs such as aluminum sulfate, magnesium aluminum carbonate and other drugs for gastric mucosal protection. 2. Eradication of Helicobacter pylori treatment: chronic atrophic gastritis is mostly related to Helicobacter pylori infection, patients need to carry out eradication of Helicobacter pylori treatment, such as clarithromycin, metronidazole, omeprazole and bismuth pectin four kinds of drugs used in combination. 3. Surgical treatment: If patients with chronic atrophic gastritis develop high-level intraepithelial neoplasia or carcinoma, endoscopic treatment or surgical treatment should be carried out under doctor’s advice, and regular follow-up. For patients with chronic atrophic gastritis, the above drugs should not be used without authorization, and need to be used under the guidance of a doctor to avoid adverse consequences.