Dryness and pain in the nose may be due to dry indoor air, dry rhinitis or atrophic rhinitis, nasal vestibulitis and so on. It is recommended that patients seek timely medical treatment, and targeted treatment under the advice of the doctor. 1. Dry indoor air: dry nose pain caused by dry indoor air can be relieved by placing a humidifier indoors to increase air humidity. 2. Rhinitis: dry rhinitis or atrophic rhinitis, nasal secretions are reduced, dryness and pain can occur. You can use a cotton swab dipped in saline, liquid paraffin, etc. to clean the nasal secretions, and then choose sensitive antibiotics, such as cefadroxil. 4. Nasal vestibulitis: the pain of patients with nasal vestibulitis is more obvious, the treatment should first remove the harmful substances in the nasal cavity, the acute stage can be used with warm saline wet compresses, with the use of topical antibiotic ointment. In the chronic stage, it is advisable to use 3% hydrogen peroxide solution to remove scabs and pus, and then apply antibiotic ointment; for those with more exudation, use 5% zinc oxide ointment to rub. Patients with dry and painful nose are advised to seek timely medical treatment and medication as prescribed by the doctor.