Depending on whether there are other clinical manifestations, deep lines on one side are considered to be related to individual differences and disease states. 1. Individual differences: everyone’s face cannot be completely symmetrical, with age, as well as sleeping posture, chewing habits, etc., may lead to a certain side of the deeper lines, but usually there is no other discomfort except for one side of the deep lines this performance. 2. Disease status: If there is leakage of wind in speech, asymmetry of headline, crooked mouth, etc., it is necessary to consider whether there is the possibility of facial paralysis. The facial paralysis side of the striae is shallower than the normal side, so it appears that the striae on one side are deep. If unilateral deep lines are accompanied by other symptoms, it is recommended to consult a doctor for further clarification of the cause of the disease.