Holistic supportive treatment for malignant tumors refers to the treatment of regulating the overall functions of patients during and after the failure of anti-cancer treatment. It includes the control of cancer pain, the support of nutrition for tumor patients, the maintenance of important organ functions, the rehabilitation of somatic functions, and the spiritual and psychological support. The purpose is to prolong the survival time of malignant tumor patients and improve the quality of life of malignant tumor patients. It is also a new concept in the field of malignant tumor treatment. Only when the overall function of cancer patients is in the best condition, can they better tolerate the related side effects brought by anti-cancer treatment, enhance the body’s immunity against tumors, and prolong the survival period of cancer patients under the premise of improving the quality of life. The Pain Medicine Center of General Hospital, with its multidisciplinary advantages, carries out overall supportive treatment for malignant tumors and formulates individualized supportive treatment plans for each cancer patient at different stages, including: 1. Control of cancer pain: standardized drug treatment, minimally invasive interventions for cancer pain and neuromodulation therapy; 2. Nutritional support: individualized nutritional support tailored for different cancer patients; 3. Maintenance of important organ functions: including immunity, blood, heart and lung, gastrointestinal, liver and kidney functions; 4. Rehabilitation of physical functions: rehabilitation of neurological and motor functions; 5. The holistic support treatment for malignant tumors brings a new treatment concept for cancer patients. We will work together to fight against the common enemy of mankind, “malignant tumor”.