Secondary cerebral infarction refers to the blockage of cerebral blood vessels caused by certain diseases, while the cerebral blood vessels themselves do not have obvious lesions, commonly found in atrial fibrillation, cardiac valvulopathy, myocardial infarction, atrial mucosarcoma, mitral valve prolapse and other cardiac diseases, as well as rheumatic and immune disorders, such as vasculitis, connective tissue disease, etc. In addition, hematological disorders can be secondary to cerebral infarction. Secondary cerebral infarction has more severe symptoms and rapid progression of the disease, and patients often present with symptoms such as impaired consciousness, complete hemiparesis and sensory deficits, complete gaze, aphasia, bulbar palsy, ataxia, and so on. Intravenous thrombolysis and thrombolysis are the first choice for these patients, and at the same time, antiplatelet, brain cell protection and improvement of cerebral circulation should be combined with other therapeutic means, and decompression surgery is feasible when necessary. Overall, the prognosis of secondary cerebral infarction is poor, with high mortality and disability rates.