How to treat cancerous pleurisy firstly, we should clarify the cause of the disease and treat the cause, followed by symptomatic treatment for the symptoms of pleurisy. 1. Treatment of the cause of the disease: Cancer pleurisy is overwhelmingly caused by pleural mesothelioma, lung cancer, breast cancer, esophageal cancer, gastric cancer, hepatocellular carcinoma and other malignant tumors, first of all, we have to clarify the etiology and carry out multidisciplinary therapeutic evaluation, if there are indications for surgery, we can carry out comprehensive treatment such as surgical tumor resection and postoperative chemotherapy, if there are contraindications to surgery, then we can adopt comprehensive treatment such as radiotherapy, targeting, immunotherapy and so on. 2. Symptomatic treatment for pleurisy (1) Analgesia: when the pain of cancerous pleurisy is severe, analgesic treatment should be given. (2) Thoracic cavity local perfusion chemotherapy: reduce exudation and pleural effusion formation, which can relieve pleural pain and reduce protein and nutrient loss in pleural fluid. (3) Closed pleural drainage is needed if the amount of pleural effusion is large to reduce symptoms of compression such as dyspnea and coughing. (4) If combined with chest infection need to give anti-infection treatment. Cancer pleurisy, it is recommended to go to the hospital for treatment in time.