Wearing protection and wearing condoms significantly reduces the risk of syphilis transmission, but is not a complete protection from infection. Wearing condoms can effectively reduce the risk of syphilis infection, but it is not 100% syphilis prevention. Syphilis is a chronic systemic sexually transmitted disease caused by syphilis spirochete infection, syphilis spirochete infection of the human body, can be spread through the blood to all organs of the body, skin and mucous membranes, and some bodily fluids, such as saliva, semen, vaginal secretions, etc., can have the presence of syphilis spirochetes. However, if the syphilis patient in addition to the genital area, other parts of the syphilis also have active skin lesions, even including the oral cavity, broken mucous membranes, etc. inside the syphilis spirochetes exist, also infectious, the use of condoms will not be able to prevent. Moreover, condoms cannot completely cover all external genitalia, skin and mucous membranes. So wearing a condom does not ensure complete safety from infection. It is recommended to avoid high-risk sexual life, if there is a history of high-risk exposure, go to the hospital specialist consultation and examination.