The treatment principles of herpes simplex are antiviral, prevention and control of secondary infections, and shortening the course of the disease, and its treatment includes: 1, relatively minor recurrent infections: simply can use dry astringent, antiviral and anti-infection-based topical creams, such as acyclovir or penciclovir, interferon, and glyburide lotion; 2, more serious primary infections: can take oral acyclovir, famciclovir, vaxilovir and other nucleoside antivirals; 3, blisters break vesicles oozing: wet compresses with boric acid solution or iodophor solution; 4, secondary bacterial infections on the vesicles: antibiotic creams such as Bactroban or erythromycin ointment.