Self-testing during outbreak prevention and control generally refers to self-testing for new crown antigen. A two-bar test for the flu does not confirm the diagnosis of neocollagenesis, and there is a possibility of false positives, which need to be confirmed by nucleic acid testing. Neocoronavirus antigen has two bands, “C” and “T”. If there are two bars, it suggests that the neocoronavirus antigen is positive, and it is possible to diagnose neocoronavirus pneumonia, but there is a possibility of false positives. The sensitivity of the new coronavirus antigen test is not very high, and the final diagnosis needs to be determined by the results of the nucleic acid test. The novel coronavirus antigen test cannot be used to confirm the diagnosis of novel coronavirus infection. The novel coronavirus antigen test is suitable for testing specific groups of people and is a complementary means of detecting novel coronavirus infections, and has the ability to improve the early detection of novel coronavirus infections, but the nucleic acid test is the only way to confirm the diagnosis of novel coronavirus infections. If there are symptoms of a cold and the antigen test results are positive on their own, this situation requires isolation measures, followed by nucleic acid testing. If the nucleic acid test is negative, centralized isolation is still required, and the patient will be closely monitored for symptoms, during which serial nucleic acid tests will be performed. If the nucleic acid antigen test is positive, and the nucleic acid test is also positive, it is a confirmed patient, then need to be isolated for treatment. Note: The terms “new coronary pneumonia and new coronary virus pneumonia” mentioned in this article were renamed to “new coronary virus infection” on December 26, 2022, as announced by the National Health Commission.