Hiccups are a physiologically common phenomenon. Hiccups are caused by involuntary contraction (spasm) of the diaphragm, which rapidly draws air into the lungs and suddenly narrows the cleft between the two vocal cords, thus causing a strange sound. According to its location, the causes can be divided into: 1. Loss of inhibition of the central hiccup reflex arc. The most important organic lesions are in the brain, including brain tumors, cerebrovascular accidents, encephalitis, meningitis, metabolic lesions such as uremia, alcoholism, and others such as multiple sclerosis. 2. Stimulation of the centripetal path of the peripheral diaphragmatic reflex arc. Stimulation of the phrenic nerve includes mediastinal tumors, esophagitis, esophageal cancer, thoracic aortic aneurysm, etc. Peridiaphragmatic lesions such as pneumonia, pleurisy, pericarditis, myocardial infarction, subdiaphragmatic abscess, esophageal hiatal hernia, etc. Vagus nerve stimulation includes gastric dilatation, gastritis, gastric cancer, pancreatitis, etc. 3. Other factors include pharmacological general anesthesia, postoperative psychiatric factors, etc. Inner ear and vestibular lesions can also cause hiccups.